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Proteomics Facility

The Proteomics Facility has been operating in its current form since 2014 and provides analytical support for diverse research and commercial projects.

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Introduction to the facility

A Sciex TripleTOF 6600 mass spectrometer is the primary instrument for LC-MS-MS analysis in the laboratory and both data-dependent and data-independent methods are utilised.

Experimental sample types range from protein gel bands through affinity-purified proteins with interacting partners to complex cell lysates. The lab has expertise in sample preparation, digestion and clean-up prior to mass spectrometry and can advise as necessary on these important aspects of experimental design. In addition to bottom-up discovery-type experiments, the facility has the capability for quantitative proteomic experiments using peptide label (iTRAQ) or label-free (SWATH) approaches.
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Sciex TripleTOF 6600 mass spectrometer

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Contact research facility manager, Dr Adrian Brown, to find out more about research services and project collaborations available

Bioanalytics Facility

Department of Biosciences

Stockton Road

Durham

DH1 3LE

Tel: +44 (0)191 334 1375 / 1301

Email: biosci.mslab@durham.ac.uk