Staff profile

Journal Article

• Diepold, N., Reese, F., Prior, T., Schnepel, C., Sewald, N., & Kottke, T. (online). Balance between photoreduction efficiency, cofactor affinity, and allosteric coupling of halogenase flavoenzymes. Photochemical & Photobiological Sciences, https://doi.org/10.1007/s43630-024-00670-y
• Willmott, M., Finnigan, W., Birmingham, W. R., Derrington, S. R., Heath, R. S., Schnepel, C., Hayes, M. A., Smith, P. D., Falcioni, F., & Turner, N. J. (online). An engineered aldolase enables the biocatalytic synthesis of 2′-functionalized nucleoside analogues. Nature Synthesis, https://doi.org/10.1038/s44160-024-00671-w
• Hogg, B. N., Schnepel, C., Finnigan, J. D., Charnock, S. J., Hayes, M. A., & Turner, N. J. (2024). The Impact of Metagenomics on Biocatalysis. Angewandte Chemie International Edition, 63(21), Article e202402316. https://doi.org/10.1002/anie.202402316
• Casamajo, A. R., Yu, Y., Schnepel, C., Morrill, C., Barker, R., Levy, C. W., Finnigan, J., Spelling, V., Westerlund, K., Petchey, M., Sheppard, R. J., Lewis, R. J., Falcioni, F., Hayes, M. A., & Turner, N. J. (2023). Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters. Journal of the American Chemical Society, 145(40), 22041-22046. https://doi.org/10.1021/jacs.3c07010
• Yu, Y., Rué Casamajo, A., Finnigan, W., Schnepel, C., Barker, R., Morrill, C., Heath, R. S., De Maria, L., Turner, N. J., & Scrutton, N. S. (2023). Structure-Based Design of Small Imine Reductase Panels for Target Substrates. ACS Catalysis, 13(18), 12310-12321. https://doi.org/10.1021/acscatal.3c02278
• Schnepel, C., Moritzer, A., Gäfe, S., Montua, N., Minges, H., Nieß, A., Niemann, H. H., & Sewald, N. (2023). Enzymatic Late‐Stage Halogenation of Peptides. ChemBioChem, 24(1), Article e202200569. https://doi.org/10.1002/cbic.202200569
• Schnepel, C., Pérez, L. R., Yu, Y., Angelastro, A., Heath, R. S., Lubberink, M., Falcioni, F., Mulholland, K., Hayes, M. A., Turner, N. J., & Flitsch, S. L. (2023). Thioester-mediated biocatalytic amide bond synthesis with in situ thiol recycling. Nature Catalysis, 6(1), 89-99. https://doi.org/10.1038/s41929-022-00889-x
• Lubberink, M., Finnigan, W., Schnepel, C., Baldwin, C. R., Turner, N. J., & Flitsch, S. L. (2022). One‐Step Biocatalytic Synthesis of Sustainable Surfactants by Selective Amide Bond Formation. Angewandte Chemie International Edition, 61(30), Article e202205054. https://doi.org/10.1002/anie.202205054
• Romero, E., Jones, B. S., Hogg, B. N., Rué Casamajo, A., Hayes, M. A., Flitsch, S. L., Turner, N. J., & Schnepel, C. (2021). Enzymatic Late‐Stage Modifications: Better Late Than Never. Angewandte Chemie International Edition, 60(31), 16824-16855. https://doi.org/10.1002/anie.202014931
• Schnepel, C., Dodero, V. I., & Sewald, N. (2021). Novel Arylindigoids by Late‐Stage Derivatization of Biocatalytically Synthesized Dibromoindigo. Chemistry - A European Journal, 27(17), 5404-5411. https://doi.org/10.1002/chem.202005191