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BIOL50415: Modelling in Molecular Biology

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Type	Tied
Level	5
Credits	15
Availability	Available in 2024/2025
Module Cap	None.
Location	Durham
Department	Biosciences

Prerequisites

None

Corequisites

None

Excluded Combinations of Modules

None

Aims

To provide students with a broad understanding of modelling in molecular biology.
To provide students with the knowledge and skills of kinetic modelling.
To provide students with the knowledge and skills of COPASI modelling environment.
To provide students with the knowledge and skills to analyse metabolic and signalling networks.
To provide students with the knowledge and skills to use kinetic modelling to develop a research project.

Content

Introduction to modelling in molecular biology.
COPASI modelling environment.
Modelling analysis of enzymatic kinetics.
Modelling analysis of regulation in biological systems.
Modelling analysis of metabolic and signalling networks.

Learning Outcomes

Subject-specific Knowledge:

Essential knowledge of enzymatic kinetics.
Essential knowledge of kinetic modelling.
Essential knowledge of COPASI modelling environment.
Essential knowledge of biological regulation.
Essential knowledge of metabolic and signalling networks.

Subject-specific Skills:

Ability to derive enzymatic kinetics.
Ability to formulate equations for kinetic modelling.
Ability to use COPASI environment to do modelling analysis.
Ability to analyse biological regulation using modelling analysis.
Ability to model metabolic and signalling networks.
Ability to develop research project using modelling analysis.

Key Skills:

Modelling analysis, visualization and interpretation
COPASI modelling environment
Hypothesis building
Problem solving

Modes of Teaching, Learning and Assessment and how these contribute to the learning outcomes of the module

This module will be delivered via lectures and workshops
Summative assessment will be via coursework.

Teaching Methods and Learning Hours

Activity	Number	Frequency	Duration	Total	Monitored
Lectures	8	Twice per week	2 hours	16	Yes
Workshops	8	Twice per week	2 hours	16	Yes
Preparation and reading				118
Total				150

Summative Assessment

Component: Coursework		Component Weighting: 100%
Element	Length / Duration	Element Weighting	Resit Opportunity
Modelling Task Report		40
Mini Project Report		60

Formative Assessment

More information

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